Junken Aoki Selected Research

Lysophosphatidylcholines (Lysophosphatidylcholine)

1/2022	Persistent elevation of lysophosphatidylcholine promotes radiation brain necrosis with microglial recruitment by P2RX4 activation.
1/2022	Lysophosphatidylcholine mediates fast decline in kidney function in diabetic kidney disease.
11/2019	Alteration of the lysophosphatidic acid and its precursor lysophosphatidylcholine levels in spinal cord stenosis: A study using a rat cauda equina compression model.
1/2019	Evaluation of Lysophospholipid Measurement in Cerebrospinal Fluid Samples using Liquid Chromatography-Tandem Mass Spectrometry.
1/2018	Autotaxin-Lysophosphatidic Acid Pathway in Intraocular Pressure Regulation and Glaucoma Subtypes.
1/2018	Lysophosphatidic acid is associated with neuropathic pain intensity in humans: An exploratory study.
1/2018	Measurement of plasma choline in acute coronary syndrome: importance of suitable sampling conditions for this assay.
9/2012	Synthetic biotinylated peptide compound, BP21, specifically recognizes lysophosphatidylcholine micelles.
11/2010	Autotaxin and lysophosphatidic acid1 receptor-mediated demyelination of dorsal root fibers by sciatic nerve injury and intrathecal lysophosphatidylcholine.
11/2009	Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: an initiator of nerve injury-induced neuropathic pain.

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Junken Aoki Research Topics

Disease

41	Neoplasms (Cancer) 05/2022 - 07/2002
14	Inflammation (Inflammations) 01/2022 - 06/2002
10	Fibrosis (Cirrhosis) 01/2020 - 09/2007
9	Neuralgia (Stump Neuralgia) 01/2019 - 02/2008
7	Neoplasm Metastasis (Metastasis) 05/2022 - 07/2007
7	Pain (Aches) 01/2021 - 01/2008
7	Melanoma (Melanoma, Malignant) 05/2018 - 06/2006
6	Colorectal Neoplasms (Colorectal Cancer) 05/2022 - 10/2004
6	Atherosclerosis 01/2022 - 01/2008
6	Ovarian Neoplasms (Ovarian Cancer) 03/2016 - 01/2002
5	Hepatocellular Carcinoma (Hepatoma) 04/2020 - 12/2003
5	Liver Cirrhosis (Hepatic Cirrhosis) 07/2018 - 09/2007
5	Acute Coronary Syndrome 01/2018 - 02/2015
4	Diabetic Nephropathies (Diabetic Nephropathy) 01/2022 - 01/2016
4	Colonic Neoplasms (Colon Cancer) 11/2021 - 10/2010
3	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 01/2013
3	Lymphoma (Lymphomas) 01/2022 - 10/2008
3	Schizophrenia (Dementia Praecox) 12/2021 - 01/2018
3	Mental Disorders (Mental Disorder) 11/2020 - 01/2018
3	Glaucoma 01/2018 - 01/2017
3	Stable Angina 09/2017 - 02/2015
3	Stomach Neoplasms (Stomach Cancer) 01/2017 - 12/2004
3	Carcinogenesis 08/2015 - 04/2005
3	Pathologic Processes 10/2010 - 05/2002
3	Prostatic Neoplasms (Prostate Cancer) 09/2009 - 07/2004
3	Lissencephaly 10/2007 - 04/2003
2	Vascular Diseases (Vascular Disease) 01/2022 - 09/2017
2	Contact Dermatitis (Eczema, Contact) 01/2022 - 01/2018
2	Necrosis 01/2022 - 08/2011
2	Endometriosis 10/2021 - 11/2019
2	Diabetes Mellitus 01/2021 - 07/2018
2	Graves Disease (Basedow Disease) 04/2020 - 05/2019
2	Coronary Disease (Coronary Heart Disease) 01/2020 - 12/2019
2	Glioblastoma (Glioblastoma Multiforme) 10/2019 - 06/2006
2	Insulin Resistance 10/2019 - 10/2012
2	Carcinoma (Carcinomatosis) 01/2019 - 01/2004
2	Non-alcoholic Fatty Liver Disease 07/2018 - 09/2010
2	Blister (Bulla) 01/2018 - 01/2017
2	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 01/2015 - 10/2008
2	Liver Diseases (Liver Disease) 01/2015 - 06/2011
2	Hypotrichosis 10/2012 - 05/2010
2	Demyelinating Diseases (Demyelinating Disease) 11/2010 - 02/2008
2	Breast Neoplasms (Breast Cancer) 03/2010 - 01/2004
1	Colitis-Associated Neoplasms 05/2022
1	Ulcerative Colitis 05/2022
1	Head and Neck Neoplasms (Head and Neck Cancer) 01/2022
1	Brain Neoplasms (Brain Tumor) 01/2022

Drug/Important Bio-Agent (IBA)

39	lysophosphatidic acidIBA 12/2021 - 07/2002
19	EnzymesIBA 01/2022 - 06/2006
16	LysophospholipidsIBA 05/2022 - 01/2002
15	Proteins (Proteins, Gene)FDA Link 12/2021 - 10/2003
15	Lysophosphatidic Acid ReceptorsIBA 01/2020 - 01/2002
15	alkylglycerophosphoethanolamine phosphodiesteraseIBA 01/2018 - 07/2002
14	LipidsIBA 01/2022 - 09/2006
14	Lysophosphatidylcholines (Lysophosphatidylcholine)IBA 01/2022 - 04/2004
14	Biomarkers (Surrogate Marker)IBA 01/2021 - 11/2010
11	Phospholipids (Phosphatides)FDA LinkGeneric 05/2022 - 05/2002
9	Messenger RNA (mRNA)IBA 11/2019 - 01/2004
7	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 10/2021 - 01/2015
7	Phospholipases A1 (Phospholipase A1)IBA 09/2021 - 03/2015
7	lysophosphatidylserineIBA 04/2020 - 01/2015
7	AntigensIBA 07/2018 - 02/2008
6	PhosphatidylserinesIBA 01/2021 - 03/2015
6	SphingosineIBA 03/2020 - 01/2016
5	Choline (Choline Chloride)IBA 01/2018 - 07/2007
4	CytokinesIBA 05/2022 - 01/2019
4	Adenosine Triphosphate (ATP)IBA 11/2021 - 01/2017
4	Pharmaceutical PreparationsIBA 01/2021 - 01/2017
4	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2020 - 08/2013
3	LigandsIBA 01/2021 - 01/2017
3	EicosanoidsIBA 01/2021 - 04/2005
3	Hexosaminidases (Hexosaminidase)IBA 10/2020 - 01/2018
3	SphingolipidsIBA 03/2020 - 12/2019
3	AlbuminsIBA 03/2020 - 01/2017
3	CeramidesIBA 03/2020 - 01/2018
3	Protein Isoforms (Isoforms)IBA 05/2019 - 01/2015
3	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 07/2010 - 03/2003
3	Biological ProductsIBA 09/2009 - 09/2006
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 05/2019
2	Monoclonal AntibodiesIBA 01/2022 - 10/2004
2	Phospholipases A2 (Phospholipase A2)IBA 01/2022 - 05/2010
2	Serotonin (5 Hydroxytryptamine)IBA 12/2020 - 12/2015
2	Transforming Growth Factors (Transforming Growth Factor)IBA 10/2020 - 08/2011
2	Indicators and Reagents (Reagents)IBA 04/2020 - 01/2016
2	sphingosine kinaseIBA 11/2019 - 01/2016
2	Glycoproteins (Glycoprotein)IBA 10/2019 - 09/2012
2	lysophosphatidylinositolIBA 05/2019 - 01/2017
2	lysophosphatidylglycerolIBA 05/2019 - 01/2017
2	Interleukin-2 Receptors (IL 2 Receptor)IBA 01/2019 - 10/2008
2	Hyaluronic Acid (Hyaluronan)IBA 07/2018 - 06/2011
2	Phosphotransferases (Kinase)IBA 01/2018 - 01/2016
2	LyasesIBA 01/2018 - 01/2016
2	Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)IBA 09/2012 - 07/2007
2	Conditioned Culture MediaIBA 09/2012 - 07/2010
2	nucleotide pyrophosphataseIBA 07/2010 - 03/2003
2	mouse LPAR6 proteinIBA 05/2010 - 09/2008
2	CalciumIBA 11/2004 - 12/2003

Therapy/Procedure

7	Therapeutics 01/2022 - 01/2002
3	Drug Therapy (Chemotherapy) 11/2021 - 03/2016
3	Spinal Injections 11/2010 - 11/2009